Varicella-Zoster Virus Antibodies, IgG and IgM
Ordering Recommendation
May aid in diagnosing acute infections and detecting past exposure and/or vaccination.
New York DOH Approval Status
Specimen Required
Serum separator tube.
Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP standard transport tube. (Min: 0.2 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or "convalescent."
Refrigerated.
See individual components.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay/Semi-Quantitative Chemiluminescent Immunoassay
Performed
Sun-Sat
Reported
1-5 days
Reference Interval
Test Number |
Components |
Reference Interval |
---|---|---|
Varicella-Zoster Virus Antibody, IgM | 0.90 ISR or less |
Interpretive Data
Component Result |
Interpretation |
---|---|
Varicella-Zoster Virus Antibody, IgG | <1.0 S/CO: Negative. No significant level of detectable varicella-zoster IgG antibody. >=1.0 S/CO: Positive. IgG antibody to varicella-zoster detected, which may indicate a current or past varicella-zoster infection. |
Varicella-Zoster Virus Antibody, IgM | 0.90 ISR or less: Negative - No significant level of detectable varicella-zoster virus IgM antibody. 0.91-1.09 ISR: Equivocal - Repeat testing in 10-14 days may be helpful. 1.10 ISR or greater: Positive - Significant level of detectable varicella-zoster virus IgM antibody. Indicative of current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection or immunization. |
FDA
Note
Hotline History
Hotline History
CPT Codes
86787 x2
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0050167 | Varicella-Zoster Virus Ab, IgG | |
0099314 | Varicella-Zoster Virus Antibody, IgM | 5404-9 |
Aliases
- Herpes Zoster
- Varicella Zoster Virus
- VZV
- VZV Antibodies, IgG & IgM
- VZV antibody panel
- VZV panel